NEW COMPONENTS OF ALCEA NUDIFLORA EXTRACT AFTER MICROWAVE EXTRACTION

Abstract

Alcea nudiflora (Lindl.) Boiss. (Malvaceae) has a wide area of growth in Central Asia, the Altai territory and Western Siberia and has long been used in folk and traditional medicine. Availability of the resource and long-term application practice makes Alcea nudiflora a promising source of valuable biologically active natural compounds. The chemical composition of A nudiflora has been studied after effective microwave assisted extraction (MAE) performed using solvents with different ability to convert microwave energy into heat: hexane, ethyl acetate, methyl tert-butyl ether (MTBE) and ethyl alcohol (EtOH). The selected MAE conditions enabled us to reduce significantly the extraction time and obtain extracts enriched with new compounds. The chemical composition of aboveground part extracts of Alcea nudiflora (Lindl.) Boiss was studied by applying GC/MS method. 13 acids were discovered for the first time, including 6 aromatic acids and 7 unbranched monobasic acids of unsaturated and saturated series, as well as 11 new neutral compounds, including 7 naphthalene derivatives.