Methods for Assessing the Severity of Adhesions in the Experiment and Clinical Setting

Author:

Sergeev Alexey NikolaevichORCID,Morozov Artem MikhailovichORCID,Epifanov Nikolay YurievichORCID,Rachek Andrei MORCID,Kerimova MerjenORCID

Abstract

The paper highlights major known approaches for an objective assessment of the severity of the adhesive process in the abdominal cavity. The scales used in experimental studies in vivo and in the clinic are considered separately. Considering various goals and objectives of experimental study, a wide range of scales has been proposed, taking into account the type of animals, the degree of the surgical zone involvement in the adhesive process, deformation of a hollow organ, degree of prevalence of the process in the abdominal cavity, adhesion density and shape, their vascularization, or a combination of the above criteria. The most universal scale applied in the clinical setting is Peritoneal Adhesion Index (PAI), which takes into account the severity and prevalence of the adhesive process, and the physical properties of peritoneal adhesions. To satisfy the objectives of a clinical study, simplified (Nair et al.) or more detailed scales (Ayushinova N.I. and co-authors) characterizing an adhesive process can be applied with a high degree of objectivity and informative.

Publisher

VSMU N.N. Burdenko

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference38 articles.

1. Yevtushenko DA. Prevention of adhesive process in patients operated on abdominal organs. Vestnik neotlozhnoi i vosstanovitel'noi meditsiny. 2013; 4:14: 459-461. (in Russ.)

2. The Small Molecule Inhibitor QLT-0267 Decreases the Production of Fibrin-Induced Inflammatory Cytokines and Prevents Post-Surgical Peritoneal Adhesions

3. Sokolova TF, Skalsky SV, Zyryanov SK. Some molecular mechanisms of the adhesive process development (Experimental study). Uspekhi sovremennoi nauki. 2017; 2:12: 35-39. (in Russ.)

4. Adhesive disease of the abdominal cavity

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3