The metabolic syndrome as factor of additional cardio vascular risk under ischemic heart disease

Abstract

The sampling of 331 patients with ischemic heart disease was included in the study to evaluate biochemical, immunologic indicators of blood, affective condition. The analysis of blood serum of patients with ischemic heart disease revealed presence of increased levels of total cholesterol, triglycerides, leptin, insulin, HOMA-IR index, total oxidizing ability of blood, oxidized low-density lipoproteins, proinflammatory cytokines interleukins-1, interleukins-6, tumor necrosis factor, adrenocorticotrophic hormone, cortisol, lowered content of total cholesterol high-density lipoproteins, total antioxidant activity of blood, superoxiddismutase. Also, increased level of depression was established, especially expressed in case of presence of concomitant metabolic syndrome.