Author:
Kuznetsova Yulia Dmytriеvna,Balashova L. M,Bykovskaya S. N
Abstract
Violation of the regulation of congenital immune reactions plays an important role in the etiology of common and serious neonatal complications in prematurely born children such as bronchopulmonary dysplasia, necrotizing enterocolitis, retinopathy of prematurity and others. This review is devoted to the study of one of the indicators of cellular immunity - T-regulatory cells CD4 + CD25 + FoxP3 + CD127low in prematury infants. Further studies of immunity and in particular T-regulatory cells in premature infants in various diseases, including retinopathy of prematurity, will further develop pathogenetically substantiated correction of immunological disorders to prevent their occurrence and progression.