NUTRITIONAL SUPPORT FOR CYSTIC FIBROSIS: THE EXPERIENCE OF THE INTRODUCTION OF DOMESTIC SPECIALIZED ENTERAL NUTRITION MIXTURES

Abstract

Background. Adequate nutritional support is known to help to avoid the protein-energy deficiency in patients with cystic fibrosis (CF) and to reduce the number of escalations of the bronchopulmonary process. The CF patients need for increased protein and energy in their diet so they need to use specialized high-calorie high-protein foods. Purpose. To estimate tolerance and clinical efficacy of specialized mixtures «Nutrien Standart» and «Nutrien Diabet» (dry and liquid forms) in CF patients over 1 year. Materials and methods. 87 children aged 1.2-17 years were observed at children’s clinics in Moscow, Tumen, Voronezh. In all cases, there was confirmed a diagnosis of CF and/or CA associated with diabetes mellitus (DM). All of them showed a nutritional deficiency of varying severity. 70% of children received liquid forms of products, 30% - dry mixtures prepared in isocaloric dilution. The WHO-Anthro and WHO-Anthro Plus programs were used for the determination of nutritional status. The duration of observation accounted for at least 2 months. Results. The taste of the products was rated by most (97.7%) patients as very good, only two (2.3%) patients refused to accept new products. No adverse events were noted during the observateon. 73 (83%) patients showed a positive dynamics of nutritional status. Among patients aged less than 6 years, the number of children with normal physical development significantly increased (p <0.05). Conclusion. The various forms of specialized domestic high-calorie high-protein products is effective for correcting the nutritional status of the CF patients over 1 year.