ANTIBACTERIAL EFFECTS OF NANOPARTICLES OF METALS

Abstract

All-new bactericidal solutions to be used in dentistry, maxillofacial surgery, urology, obstetrics, gynaecology, ENT, proctology have been developed. By means of electric impulse and disperse condensate means, water and alcoholic (ethanolic) colloidal nanodispersed systems of metals have been procured and also their oxides based on: argentum (Ag), titanium dioxide (TiO), ferrous oxide (FeO), tantalum oxide (TaO), vanadium oxide (VO2), cobaltous oxide (CoO), tantalum dioxide TaO2, zink oxide (ZnO), cupric oxide (CuO), a mixed solution of: titanium dioxide (TiO), aluminium oxide (Al2O) and molybdenum dioxide (MoO). The research has been made on culture of dentobacterial plaque and mixed culture, issued from gingival spaces. The composition of culture was identified with S. aureus, S. epidermidis and nonfermentable kinds of E. coli. The observation period lasted more than nineteen days. All solutions showed highly prolonged bactericidal activity in dilutions from the whole solution 1-20 mg/L. Dilution step is tenfold (10-1; 10-2; IO-'; 10-4; 10-5; 10-6; 10-7). The bactericidal activity ofpowder specimen of glass, used to produce dental filling material and disintegrates of composite materials, issued by «StomaDent» CJSC, processed by Ag and FeO2 nanoparticles, have been studied. Tested materials have long, up to 19 days and more, bactericidal activity.