Modern approaches to the diagnosis and treatment of microscopic polyangiitis.

Author:

Shchegoleva Elena M.1ORCID,Zykova A. S.2,Bulanov N. M.1,Novikov P. I.1,Moiseev S. V.3ORCID,Mukhin N. A.3ORCID

Affiliation:

1. I.M. Sechenov First Moscow state medical University (Sechenov University)

2. M.V. Lomonosov Moscow state University

3. I.M. Sechenov First Moscow state medical University (Sechenov University); M.V. Lomonosov Moscow state University

Abstract

Microscopic polyangiitis (MPA) is the form of ANCA-associated vasculitis, characterized by pulmonary and kidney damage. This article discusses a case of severe MPA in a young patient and is focused on the modern diagnostic and treatment approaches. The authors also review different clinical courses and outcomes of MPA.

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

Reference30 articles.

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2. Jennette J.C., Falk R.J., Bacon P.A., Basu N., Cid M.C., Ferrario F. et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of vasculitides. Arthritis Rheum. 2013; 65(1): 1-11.

3. Falk R.J., Moore D.T., Hogan S.L., Jennette J.C. A renal biopsy in essential for the management of ANCA-positive patients with glomerulonephritis. Sarcoidosis Vasc. Diffuse Lung Dis. 1996; 13(3): 230-1.

4. Berden A.E., Ferrario F., Hagen E.C., Jayne D.R., Jennette J.C., Joh K.et al. Histopathologic classification of ANCA-associated glomerulonephritis. J. Am. Soc. Nephrol. 2010; 21(10): 1628-36.

5. Beketova T.V. Microscopic polyangiitis associated with antineutrophil cytoplasmic antibodies: clinical features. Terapevticheskiy arkhiv. 2015; 87(5): 33-46. (in Russian)

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1. Microscopic polyangiitis: Modern concepts and treatment options;Rheumatology Science and Practice;2021-10-31

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