The effectiveness of piribedil for the treatment of cognitive disorders in patients with coronary heart disease: results of six-month observation-Reference-Cited by-同舟云学术

The effectiveness of piribedil for the treatment of cognitive disorders in patients with coronary heart disease: results of six-month observation

Published:2017-06-08 Issue:5 Volume:95 Page:445-450
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:Klin. med.

Author:

Petrova M. M.¹,Prokopenko S. V.²,Eremina O. V.¹,Mozhejko E. Yu.²,Kaskaeva D. S.¹,Gankin M. I.²,Shevchenko O. I.³

Affiliation:

1. Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

2. Federal Centre for Cardiovascular Surgery

3. Krasnoyarsk Regional Clinical Hospital, Russia

Abstract

Aim. The detection of cognitive deficiency after heart bypass surgery, the evaluation of the influence of piribedil on the higher cerebral function in the early postoperative period during the follow-up. Materials and methods. 64 patients with ischemic heart disease were examined. They were divided into two groups. Patients of the main group (n=32) were treated with pronoran (piribedil) at a daily dose of 50 mg for 3 months. 32 patients of the control group received standard therapy in the postoperative period. All patients had undergone heart bypass surgery. Cognitive functions were examined before operation, 10 days , three and six months after surgery. Results. Positive dynamics of all tested parameters was documented in the patients of the main group within 6 months after the onset of therapy. In control patients, cognitive disorders remained at the preoperative level based on the results of three tests. Conclusion. The positive results of piribedil therapy suggest that piribedil has positive effect on memory, attention and psychomotor activity of the patients

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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