Affiliation:
1. MSMSU them. A.I. Evdokimova Ministry of health of the Russian Federation
Abstract
Cholinesterase activity in mixed saliva of patients with somatic pathology was investigated. The results showed differences in enzyme activity depending on the disease. The highest salivary cholinesterase activity was detected in patients with bronchopulmonary pathology, and the lowest - in cardiovascular diseases. A reliable relationship between the changes in the activity of cholinesterase in saliva and the rate of salivation, and with patients taking atypical antipsychotics and M, H-anticholinergic drugs, was revealed.
Subject
Biochemistry (medical),Medical Laboratory Technology,General Medicine
Reference10 articles.
1. Chessick H.I. Histochemical study of the distribution of esterases. Histochem. and Cytochem. 1953; 2: 471-85.
2. Burstone M.S. Esterase of the salivary glands. Histochem. and Cytochem.1956; 4(2):130-9.
3. Ord M.G., Thompson H.H.S. The distribution of cholinesterase types in mammahian tissues. Biochem. 1950; 46(3): 346-52.
4. Dawson L.J., Caulfield V.L., Stanbury J.B., Field A.E., Christmas S.E., Smith P.M. Hydroxychloroquine therapy in patients with primary Sjoёgren’s syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. Rheumatology. 2005; 44: 449–55.
5. Farah R., Haraty H., Salame Z., Fares Y., Ojcius D.M., Said Sadier N. Salivary biomarkers for the diagnosis and monitoring of neurological diseases. Biomed. J. 2018; 41: 63–87.