DEVELOPMENT OF A SET OF REAGENTS FOR DETECTION OF CLASS G IMMUNOGLOBULINS TO THE HUMAN HERPES VIRUS TYPE 7 BY THE METHOD OF IMMUNE BLOTTING IN THE FORMAT «WESTERN BLOT»-Reference-Cited by-同舟云学术

DEVELOPMENT OF A SET OF REAGENTS FOR DETECTION OF CLASS G IMMUNOGLOBULINS TO THE HUMAN HERPES VIRUS TYPE 7 BY THE METHOD OF IMMUNE BLOTTING IN THE FORMAT «WESTERN BLOT»

Published:2020-05-15 Issue:6 Volume:65 Page:362-367
ISSN:2412-1320
Container-title:Russian Clinical Laboratory Diagnostics
language:
Short-container-title:Klin. lab. diagn.

Author:

Mardanly S. G.¹^ORCID,Avdonina A. S.²^ORCID,Pomazanov V. V.³^ORCID

Affiliation:

1. The closed corporation «ECOlab»; The state educational institution of higher education «The state humanitarian technological university»

2. The closed corporation «ECOlab»

3. The state educational institution of higher education «The state humanitarian technological university»

Abstract

A new original domestic set of reagents has been developed for the determination of class G immunoglobulins to individual human herpes virus antigens of type 7 by the method of immune blotting in the “Western-blot” format. Preliminary clinical trials were conducted using 134 serums of healthy children aged 1-16 years who underwent diagnostic testing. Study of diagnostic efficiency of the new kit showed high sensitivity, comparable to the sensitivity of the reaction indirect immunofluorescence and high specificity, which is manifested in the absence of false positive results when testing samples containing immunoglobulin G to herpes virus 6 type.

Publisher

EKOlab

Subject

Biochemistry, medical,Medical Laboratory Technology,General Medicine

Reference28 articles.

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