CREATION OF A MOLECULAR GENETIC TEST SYSTEM FOR EARLY DIAGNOSTICS AND EVALUATION OF EFFECTIVENESS OF TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES-Reference-Cited by-同舟云学术

CREATION OF A MOLECULAR GENETIC TEST SYSTEM FOR EARLY DIAGNOSTICS AND EVALUATION OF EFFECTIVENESS OF TREATMENT OF INFLAMMATORY PERIODONTAL DISEASES

Published:2020-01-15 Issue:1 Volume:65 Page:55-60
ISSN:0869-2084
Container-title:Russian Clinical Laboratory Diagnostics
language:
Short-container-title:RCLD

Author:

Tamarova E. R.¹^ORCID,Shvets K. Yu.²^ORCID,Mavzyutov A. R.¹^ORCID,Baimiev Al. H.²^ORCID,Bulgakova A. I.¹^ORCID

Affiliation:

1. Bashkir State Medical University

2. Bashkir State Medical University; Institute of Biochemistry and Genetics of Ufa Scientific Center RAS

Abstract

Inflammatory periodontal diseases represent a serious dental and general medical problem due to the high prevalence among the adult population, the presence of clinical forms leading to the destruction of the dentition and tooth loss, insufficient treatment effectiveness and the frequency of relapse, including in connection with the formation of biofilms. A molecular genetic test system has been developed to evaluate the content of periodontopathogenic microorganisms Porphyromonas gingivalis, Treponema denticola, Streptococcus oralis, Streptococcus sanguis and Streptococcus sobrinus in the contents of periodontal pockets. The analytical characteristics of the test system were determined, and testing was carried out on clinical samples of patients with chronic generalized periodontitis of moderate severity.The constructed diagnostic kit allowed us to conduct a comparative analysis of the effectiveness of various types of treatment of inflammatory periodontal diseases based on quantitative data on the content of bacteria in the contents of periodontal pockets.

Publisher

EKOlab

Subject

Biochemistry, medical,Medical Laboratory Technology,General Medicine

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