Development of the force field for cyclosporine A
Author:
Affiliation:
1. Graduate School of Medical Life Science, Yokohama City University
Publisher
Biophysical Society of Japan
Subject
Physiology,Molecular Biology,Biophysics,Biochemistry,Biochemistry, Genetics and Molecular Biology (miscellaneous)
Link
https://www.jstage.jst.go.jp/article/biophysico/19/0/19_e190045/_pdf
Reference53 articles.
1. [1] Tamamura, H., Kobayakawa, T., Ohashi, N. Mid-size drugs based on peptides and peptidomimetics: A new drug category. SpringerBriefs in Pharmaceutical Science & Drug Development (Springer, Singapore, 2018). https://doi.org/10.1007/978-981-10-7691-6
2. [2] Ruegger, A., Kuhn, M., Lichti, H., Loosli, H. R., Huguenin, R., Quiquerez, C., et al. Cyclosporin A, a peptide metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity. Helv. Chim. Acta 59, 1075–1092 (1976). https://doi.org/10.1002/hlca.19760590412
3. [3] Wenger, R. M. Synthesis of cyclosporine and analogs - structural requirements for immunosuppressive activity. Angew. Chem. Int. Ed. Engl. 24, 77–85 (1985). https://doi.org/10.1002/anie.198500773
4. [4] Hiestand, P. C., Gubler, H. U. Cyclosporins: Immunopharmacologic properties of natural cyclosporins. in The Pharmacology of Lymphocytes. (Bray, M. A., Morley, J. eds.), pp. 487–502 (Springer Berlin Heidelberg, Berlin, Heidelberg, 1988).
5. [5] Liu, J., Farmer, J. D., Jr., Lane, W. S., Friedman, J., Weissman, I., Schreiber, S. L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807–815 (1991). https://doi.org/10.1016/0092-8674(91)90124-h
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