Unraveling T-cell dynamics using fluorescent timer: Insights from the Tocky system
Author:
Affiliation:
1. Department of Life Sciences, Imperial College London
2. Joint Research Center for Human Retrovirus Infection, Kumamoto University
Publisher
Biophysical Society of Japan
Link
https://www.jstage.jst.go.jp/article/biophysico/21/Supplemental/21_e211010/_pdf
Reference35 articles.
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3. [3] Moran, A. E., Holzapfel, K. L., Xing, Y., Cunningham, N. R., Maltzman, J. S., Punt, J., et al. T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse. J. Exp. Med. 208, 1279–1289 (2011). https://doi.org/10.1084/jem.20110308
4. [4] Ono, M. Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes. Immunology 160, 24–37 (2020). https://doi.org/10.1111/imm.13178
5. [5] Bending, D., Ono, M. From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics. Clin. Exp. Immunol. 197, 14–23 (2019). https://doi.org/10.1111/cei.13194
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