Affiliation:
1. Liberty University College of Osteopathic Medicine, Lynchburg, VA
Abstract
With close to 2 billion people affected globally, anemia is a commonly seen condition worldwide. Diagnosed by a patient’s low hemoglobin, and then subsequently differentiated through red blood cell indices, a complete blood count should be performed on every patient presenting with the classic symptoms of anemia. Iron studies, as well as the corrected reticulocyte count and peripheral blood smears, can also be of use to further specify the exact type of anemia. Additionally, tests including colonoscopies, upper endoscopies and gynecologic procedures should be considered to identify the different underlying causes of the disease. The most common microcytic anemias include iron deficiency, thalassemia and anemia of inflammation. Deficiencies in folate and B12—also known as cobalamin—are the most common etiologies of macrocytic anemia. Treatment of each of these types of anemia is tailored to the individual patient based on the severity of their condition as well as the specific underlying cause. Osteopathically, anemia falls largely into the respiratory-circulatory model, as well as the metabolic-energy model, which can also be used to guide treatment. For a family physician, identifying symptoms, making accurate diagnoses and properly treating patients with anemia is of the utmost importance.
Publisher
The American College of Osteopathic Family Physicians - ACOFP
Reference48 articles.
1. Kassebaum NJ, GBD 2013. Anemia Collaborators. The global burden of anemia. Hematol Oncol Clin North Am. 2016;30(2):247-308. doi:10.1016/j.hoc.2015.11.002
2. Chaparro CM, Suchdev PS.Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Ann N Y Acad Sci. 2019;1450(1):15–31. doi: 10.1111/nyas.14092
3. World Health Organization. Nutritional anaemias: Tools for effective prevention and control. Geneva: World Health Organization; 2017. https://www.who.int/publications/i/item/9789241513067?sequence=1.Published November 13, 2017. Accessed July 1, 2021.
4. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Geneva: World Health Organization; 2011. https://www.who.int/iris/bitstream/handle/10665/85839/WHO _N MH_NHD _MNM_11.1_eng.pdf. Accessed June 2, 2021.
5. Ning S, Zeller MP. Management of iron deficiency. Hematology Am Soc Hematol Educ Program. 2019;2019(1):315–322. doi:10.1182/hematology.2019000034