Cutaneous hemosiderosis in chronic venous insufficiency: A review-Reference-Cited by-同舟云学术

Cutaneous hemosiderosis in chronic venous insufficiency: A review

Published:2022-05-01 Issue: Volume: Page:22-26
ISSN:1877-573X
Container-title:Osteopathic Family Physician
language:en
Short-container-title:OFP

Author:

Nickles Melissa Ashley¹,Tsoukas Maria M.²,Braniecki Marylee A.³,Altman Igor⁴

Affiliation:

1. University of Illinois College of Medicine at Chicago, Chicago, IL

2. University of Illinois College of Medicine at Chicago – Dermatology, Chicago, IL

3. University of Illinois College of Medicine at Chicago – Pathology, Chicago, IL

4. University of Illinois College of Medicine at Chicago – Surgery, Chicago, IL

Abstract

Hemosiderosis is the deposition of hemosiderin, a storage form of iron derived from the breakdown of erythrocytes. This process commonly occurs in patients with chronic venous insufficiency (CVI) due to venous hypertension and vascular ectasia. Cutaneous accumulation of hemosiderin in CVI causes brown hyperpigmentation and contributes to lipodermatosclerosis and ulceration, further highlighting the pathogenic role of iron metabolism in these disorders. In this review, we examine the pathophysiology and clinical presentation of hemosiderosis in CVI, summarize its management and prevention strategies, and explore its impact on quality of life.

Publisher

The American College of Osteopathic Family Physicians - ACOFP

Subject

Family Practice

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