Eliminate spiral wave and spatiotemporal chaos by using short-term cardiac memory

Abstract

Cardiac memory effect, which exhibits the time-delayed coupling of membrane voltage, is introduced into Luo-Rudy phase I cardiac model. The effect of the cardiac memory on spiral waves is investigated. The numerical results show that the cardiac memory can lead to irregular meandering of spiral waves. When the delay-time is properly chosen, the increase of memory strength causes the decrease of spiral wave frequency. If memory strength exceeds the critical value, the cardiac memory results in the disappearances of both spiral waves and spatiotemporal chaos in system because the time-dependent potassium ion current is over suppressed by cardiac memory.