Phantom study of the classification of liver fibrosis based on nuclear magnetic resonance elasto-graphy

Abstract

Accurate detection of liver fibrosis stage and fibrosis procession is crucial for assessing prognosis and candidacy for treatment of patients with chronic hepatic disease. A significant need exists for developing a noninvasive technique for quantitative detection of liver fibrosis stage. Magnetic resonance elasto-graphy (MRE) is one of the most repidly advancing technologies for classifying the liver fibrosis. This study establishes a platform for liver fibrosis classification, and discusses some details in developing stimulator and displacement-phase imaging pulse. At last, the preliminary result and analysis of phantom experiment are given, which would form a basis for subsequent research on phantom MRE and its clinic application.