Affiliation:
1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China
2. Hubei University of Chinese Medicine, Wuhan 430065, P. R. China
3. Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming 650223, P. R. China
Abstract
Four new sesquiterpenoids, 1α-hydroxymethyl-3β-hydroxy-7,8-dihydro-ionol (1), 1α-hydroxymethyl- 3β-hydroxy-7,8-dihydro-ionol-9-O-β-D-glucopyranoside (2), (1α,5β,7β)-3,10(14)-guaiadien- 11,12-diol (3), and (6S)-13-O-β-D-glucopyranosyl-abscisic acid (4), together with 10 known sesquiterpenoids and 5 diterpenes were isolated from the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidence. Compound 13-epi-toruolsol (17) showed cytotoxicities against BGC-823 and Hela cancer cell lines with IC50 values of 23.0 and 49:9 μM, and compound 3-epitriptobenzene B (19) showed cytotoxicities against BGC-823, Hela and A549 cancer cell lines with IC50 values of 19.1, 30.3 and 24:5 μM, respectively
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6 articles.
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