Synthesis and Coordination Chemistry of a Tris(benzene-o-dithiolato)- functionalized Ligand as a Siderophore Analog

Abstract

As a siderophore analog, the tripodal tris(benzene-o-dithiol)-functionalized ligand H6-5, has been synthesized in four steps including the reaction of 1,3,5-(triaminomethyl)-2,4,6-triethylbenzene and 2,3-bis(isopropylmercapto)benzoyl chloride followed by removal of the S-protecting groups. Reaction of compound H6-5 with [Ti(OPr)4] in the presence of (NEt4)Cl leads to the formation of complex (NEt4)2[Ti(5)] featuring three bidentate benzene-o-dithiolato donors from one ligand coordinated to the metal center. An X-ray diffraction structure analysis with crystals of (NEt4)2[Ti(5)] DMF has shown that the coordination geometry at the metal center is best described as distorted trigonalprismatic with a twist angle of ϕav = 18:5°.