In vitro speciation of molybdenum in human biological samples based on thiol functionalized mesoporous silica nanoparticles and hexyl-methylimidazolium tris-pentafluoroethyl-trifluorophosphate

Author:

Ashori Roya,Hajiseyed Mirzahosseini Seyed Alireza

Abstract

Molybdenum (Mo) ions enter to human body from the diet or drinking waters and have a potentially toxic effect on humans. The thiol-functionalized mesoporous silica nanoparticles (HS-MSNPs) were used for determination and speciation of Mo (II, VI) in human biological samples by dispersive ionic liquid-micro-solid phase extraction (DIL-μ-SPE) coupled to electrothermal atomic absorption spectrometry (ET-AAS). Firstly, the mixture of HS-MSNPs (15 mg), the hydrophobic ionic liquid (1-Hexyl-3-methylimidazolium tris(pentafluoroethyl) trifluorophosphate; [HMIM][T(PFE)PF3]) and acetone injected into 10 mL of human blood and serum samples. After shaking for 5 min, the Mo(II) and Mo(VI) ions were extracted with the thiol group of MSNPs at pH 6 and 2, respectively, and collected through IL at the bottom of the conical tube by centrifuging. Then, the MO(II,VI) ions were back-extracted from HS-MSNPs with elent based on changing pH, and remained solutions were determined by ET-AAS after dilution with DW up to 0.5 mL, separately.

Publisher

SciTech Solutions

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