Myxofibrosarcoma of Head and Neck Region in a Patient with Follicular Carcinoma of Thyroid

Abstract

Myxofibrosarcoma (MFS) is a malignant fibroblastic tumour with variable myxoid stroma, cellular pleomorphism and curvilinear vascular pattern. It is commonly seen in late adult life, peaks in the seventh decade and usually occurs in the lower extremities. MFS of head and of the neck is extremely rare and accounts for approximately 1% of all head and neck neoplasms. A fifty two year old lady with follicular carcinoma thyroid treated six years ago, presented with a rapidly increasing neck swelling in the left supraclavicular fossa. Fine needle aspiration cytology of the cervical node was suggestive of metastatic carcinoma and she underwent left posterolateral neck dissection. Histopathology and immunohistochemistry was suggestive of high grade myxofibrosarcoma with negative margins. She was treated with adjuvant radiotherapy and has been under regular follow up for 6 months.