Comparative Study of CBNAAT with Sputum Microscopy by Led Microscopy & Liquid Culture in Sputum Samples of Presumptive Pulmonary Tuberculosis

Abstract

Tuberculosis is a communicable disease & a leading cause of death from a single infectious agent (ranking above HIV /AIDS). Early diagnosis is important for early patient management and successful treatment. The present study was a prospective observational study done on 84 suspected Pulmonary Tuberculosis patients visiting Government Chest disease and TB hospital Warangal during the time period of December 2017 to July 2019 & were evaluated with different microbiological tests for further confirmation of pulmonary tuberculosis .Considering liquid culture as the gold standard tool for diagnosis of Tuberculosis, sensitivity , specificity, PPV, NPV of CBNAAT were 78.4%, 60.6%, 75%, 65% respectively and sensitivity, specificity, PPV, NPV of AFB smear were 80%, 47.5%, 39%, 85% respectively in the present study.