Influence of romifidine and detomidine on the induction of anesthesia and recovery from total intravenous anesthesia in horses

Abstract

In the present study, the quality of the induction of and the recovery from anesthesia was compared in 146 horses undergoing total intravenous anesthesia with guaifenesin, ketamine and detomidine for computed tomography (CT), randomly assigned to receive either romifidine (n = 110) or detomidine (n = 36) during premedication. The induction of anesthesia was performed with a ketamine-midazolam combination. The anesthetic duration was short (mean +/- SD time: 23.5 +/- 8.8 minutes). No significant difference in induction score was observed. However, the recovery quality was significantly better in horses premedicated with romifidine.