Effect of Saturation Pulse Duration and Power on pH-weighted Amide Proton Transfer Imaging: A Phantom Study
Author:
Affiliation:
1. Division of Radiology, Department of Medical Technology, Kyushu University Hospital
2. Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University
Publisher
Japanese Society for Magnetic Resonance in Medicine
Subject
Radiology, Nuclear Medicine and imaging
Link
https://www.jstage.jst.go.jp/article/mrms/advpub/0/advpub_mp.2021-0109/_pdf
Reference20 articles.
1. 1. Zhou J, Lal B, Wilson DA, Laterra J, van Zijl PC. Amide proton transfer (APT) contrast for imaging of brain tumors. Magn Reson Med 2003; 50:1120–1126.
2. 2. Zhou J, Payen JF, Wilson DA, Traystman RJ, van Zijl PC. Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat Med 2003; 9:1085–1090.
3. 3. Togao O, Kessinger CW, Huang G, et al. Characterization of lung cancer by amide proton transfer (APT) imaging: an in-vivo study in an orthotopic mouse model. PLoS One 2013; 8:e77019.
4. 4. Togao O, Yoshiura T, Keupp J, et al. Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades. Neuro-oncol 2014; 16:441–448.
5. 5. Sagiyama K, Mashimo T, Togao O, et al. In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma. Proc Natl Acad Sci USA 2014; 111:4542–4547.
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