The Effects of Oral Progestagen Administration on the Fertility of Synchronized Goats During the Breeding Season

Author:

Çetin Nebi1ORCID,Kuru Mushap2ORCID,Koca Davut1ORCID,Eşki Funda3ORCID,Uslu Barış Atalay4ORCID,Sendag Sait5ORCID,Wehrend Axel6ORCID

Affiliation:

1. VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ

2. KAFKAS ÜNİVERSİTESİ

3. CUKUROVA UNIVERSITY

4. SIVAS CUMHURIYET UNIVERSITY

5. VAN YUZUNCU YIL UNIVERSITY

6. Justus Liebig Univercity

Abstract

The objective of this study was to assess the impact of oral progesterone (altrenogest) administered after mating on fertility in goats synchronized during the breeding season. A total of 47 Hair goats were included in the study. A progesterone-impregnated intravaginal sponges were administered for 12 days. On day 10 of intravaginal sponge administration, 480 IU pregnant mare's serum gonadotropin (PMSG) and 0.075 mg cloprostenol were injected intramuscularly to the goats. Animals were exposed to bucks for 12 hours after detection of estrus by the foraging buck. The goats were randomly assigned to two distinct groups: Group 1 (G1, n=23) and Group 2 (G2, n=24). G1 goats were orally administrated 4.4 mg of altrenogest per day for 30 days after mating. G2 goats served as controls. Pregnancy examinations were performed by transrectal ultrasonography on the 30th and 42nd days after mating. Blood samples were taken from one day after mating to 30 days (3-day intervals). Statistical analysis comparing G1 and G2 revealed no significant differences between the groups regarding progesterone concentrations, conception rate, pregnancy rate, lambing rate, multiple birth rate, fecundity, and litter size (p>0.05). In conclusion, this study revealed that oral progesterone use had no impact on fertility parameters. Moreover, further research is warranted to explore the efficacy of various oral progesterone analogs.

Funder

Van Yüzüncü Yil University, Scientific Research Projects Coordination Unit

Publisher

Van Veterinary Journal

Reference46 articles.

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2. Alcay S, Aktar A, Koca D et al. (2022b). Autologous platelet rich plasma have positive effect on ram spermatozoa during cryopreservation in non-breeding season. Kafkas Univ Vet Fak Derg, 28 (2), 229-234.

3. Arndt WJ, Holle AJ, Bauer ML et al. (2009). Effect of post-insemination progesterone supplementation on pregnancy rate in dairy cows. Can J Vet Res, 73 (4), 271-274.

4. Arosh JA, Banu SK, McCracken JA (2016). Novel concepts on the role of prostaglandins on luteal maintenance and maternal recognition and establishment of pregnancy in ruminants. J Dairy Sci, 99 (7), 5926-5940.

5. Cetin N (2021). İneklerde Embriyonik Ölümlerden Korunmada Nonsteroid Antiinflamatuar İlaç Uygulamaları ve Hormonal Girişimler. Ayvazoğlu Demir P and Kuru M (Eds). Tüm Yönleriyle İneklerde Embriyonik Ölümler ve Abortus. (p. 153-171). Akademisyen Kitabevi, Ankara.

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