Development and Validation of UV-VIS Spectrophotometric Method for Estimation of Methylprednisolone from Dissolution Media-Reference-Cited by-同舟云学术

Development and Validation of UV-VIS Spectrophotometric Method for Estimation of Methylprednisolone from Dissolution Media

Published:2024-05-25 Issue:3 Volume:11 Page:437-441
ISSN:2395-602X
Container-title:International Journal of Scientific Research in Science and Technology
language:
Short-container-title:Int J Sci Res Sci & Technol

Author:

Mhetre M. N. ,Kalshetti M. S.

Abstract

A simple, accurate UV-Spectrophotometric method has been developed using a dissolution media, 0.1% Tween 20 as a solvent to determine the methylprednisolone. At a predetermined λmax of 245 nm, method was proved linear in the range of 5-40 μg/ml with good correlation coefficient (R2=0.998) and excellent recovery (between 98 and 101%). This method was successfully applied to the determination of methylprednisolone from dissolution media, 0.1% Tween 20 aqueous solution. This method can be employed for the dissolution study of methylprednisolone in injectable suspension.

Publisher

Technoscience Academy

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