Changes In Different Structures of Eyeball in Ice Syndrome : A Review Study

Abstract

ICE syndrome (iris corneal endothelium syndrome) is a rare condition that affects the irregular corneal endothelium, which can cause varying degrees of glaucoma. The proliferative and structural abnormalities of the corneal endothelium, the increasing constriction of the iridocorneal angle, and iris abnormalities such atrophy, correctopia, and polycoria are the hallmarks of the ICE syndrome. A Narrative review was done to review the articles available on PubMed, Google Scholar, Medline, Publon, Orcid, Healthstar, and others related to ICE syndrome. Peer-reviewed articles/ studies were referred to ascertain the available screening tests, risk factors, physiological parameters, and diagnosis of glaucoma on the basis of ICE, chandler’s syndrome, progressive iris atrophy and management options for ICE syndrome. This review study provides an overview of the ICE syndrome’s complications, ocular examination, causes and about management options. Thus, the assessment can be easily done by full ophthalmic workup, with vision assessment of refractive error, slit lamp examination, intraocular pressure measurement, and fundus examination. In Gonioscopy findings we will get PAS usually extending to or beyond the schwalbe line. It is yet unknown what factors underlie corneal endothelial changes and are the primary causes of ICE syndrome. A viral aetiology has been proposed, particularly Epstein virus and Herpes simplex virus. The initial step in treating corneal oedema is to lower the intraocular pressure inside the eye.