ACETYLCHOLINESTERASE, AS A POTENTIAL BIOMARKER OF NAPHTHALENE TOXICITY IN DIFFERENT TISSUES OF FRESHWATER TELEOST, ANABAS TESTUDINEUS

Author:

Nayak Susri1,Patnaik Lipika1

Affiliation:

1. Center of Excellence in Environment and Public Health, Environmental Science Laboratory, Department of Zoology, Ravenshaw University, Cuttack 753008, Odisha, India

Abstract

Naphthalene, a Polycyclic Aromatic Hydrocarbon is widely used as a fumigant and disinfectant despite its toxic effect and is ranked as the ninth most threatening compound. The present study was carried out to determine the in vivo effect of naphthalene at different concentrations on acetylcholinesterase (AChE) enzyme activity in different tissues of Anabas testudineus. The fishes were exposed to varying concentrations of naphthalene (4.2 mgL–1, 4.4 mgL–1, 4.6 mgL–1, 4.8 mgL–1 and 5 mgL–1) for a period of 72 hours. Acetylcholinesterase enzyme activity was found to be significantly inhibited, in a dose-response manner. The inhibition percentage of AChE activity varied from 9.34–43.95% in brain tissue, 2.56–35.81% in liver tissue, 5.94–34.15% in muscle tissue and 3.92–33.75% in gills in comparison to the tissues of the control group. Maximum inhibition of acetylcholinesterase enzyme activity in treated fish was observed in the brain followed by liver, muscles, and gills. This study highlights the significance and role of acetylcholinesterase as a potential stress biomarker of naphthalene toxicity.

Publisher

Vilnius Gediminas Technical University

Subject

Management, Monitoring, Policy and Law,Nature and Landscape Conservation,Environmental Engineering

Reference45 articles.

1. Acetylcholinesterase, glutathione and hepatosomatic index as potential biomarkers of sewage pollution and depuration in fish

2. Properties of Ceramic Waste Powder-Based Geopolymer Concrete

3. American Public Health Association. (2005). Standard methods for the examination of water and wastewater. American Public Health Association/American Water Works Association/Water Environment Federation. Washington, DC.

4. Naphthalene induced activities on growth, respiratory metabolism and biochemical composition in juveniles of Metapenaeus affinis (H. Milne Edward, 1837);Ansari, Z. A.;Indian Journal of Marine Sciences,2010

5. Lung Cancer Risk after Exposure to Polycyclic Aromatic Hydrocarbons: A Review and Meta-Analysis

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