Karate Zeon Pestisitinin Mutajenik Aktivitesinin Ames Testi ile Değerlendirilmesi

Abstract

Pesticides widely used in the agricultural market led to an increase in the quality and yield of crops. However, pesticides are a major concern in the environment as they also harm non-target creatures, because of pesticide resistance, and mutagenic and carcinogenic effects. In this study, we aimed to research the potential mutagenicity of Karate Zeon which is a synthetic pyrethroid insecticide. Salmonella typhimurium mutagenicity assay (Ames test) was used to evaluate the mutagenicity of Karate Zeon insecticide in the absence and presence of the S9 fraction on two strains (TA98 and TA100). In this study, doses of 250, 25, 2.5, 0.25, 0.025 μg/plate of Karate Zeon were used. Karate Zeon pesticide showed mutagenic activity at 250 μg/plate concentration on both TA98 and TA100 with and without metabolic activation.