Author:
CEOBANU Gabriela, ,GHEORGHE Gina,IONESCU Vlad Alexandru, , , ,
Abstract
Intraductal papillary mucinous neoplasms of the pancreas (IPMNs) are precancerous lesions. Anatomically, IPMNs are classified as main duct-type and branch duct-type. Histologically, these neoplasms are grouped into 4 categories: intestinal, pancreatobiliary, oncocytic, and gastric. Patients diagnosed with IPMN have been shown to have an increased risk of malignancy of the pancreatic tumor, but also an increased risk of associating cancers with extrapancreatic localization. Among the factors associated with the risk of malignancy of IPMNs are the involvement of the main pancreatic duct or branch duct, tumor size, diameter of the main pancreatic duct, and histological type. Regarding IPMN-associated extrapancreatic cancers, gastric adenocarcinoma and colorectal adenocarcinoma were the most reported.
Publisher
Academia Oamenilor de Stiinta din Romania
Reference31 articles.
1. Mucin-secreting tumors of the pancreas; Lichtenstein;Gastrointest Endosc Clin N Am,1995
2. [2] Tanaka M, Chari S, Adsay V, et al, International Association of Pancreatology. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology. 2006;6(1-2):17.
3. [3] Hruban RH, Takaori K, Klimstra DS, et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol. 2004;28(8):977.
4. [4] Ohashi K, Murakami Y, Maruyama M. Four cases of mucin producing cancer of the pancreas on specific findings of the papilla of Vater. Prog Dig Endosc. 1982; 20:348.
5. [5] Allen PJ, D'Angelica M, Gonen M, et al. A selective approach to the resection of cystic lesions of the pancreas: results from 539 consecutive patients. Ann Surg. 2006;244(4):572.