Cervical Carcinoma of Unknown Primary Site

Abstract

Cervical carcinoma of unknown primary site is a condition characterized by the presence of a metastatic lymph node neck mass in the absence of the primary tumor, despite extensive diagnostic procedures. This condition affects more often male patients with a history of tobacco and alcohol abuse or human papilloma virus (HPV) or Epstein-Barr virus (EBV) chronic infection. The detection of the primary tumor and identification of the histopathological type have a key role in the management of patients with unknown primary tumors. Treatment is multimodal, including surgery, radiotherapy and chemotherapy.