HYDROXYAPATITE NANOPARTICLES: A REVIEW OF THEIR EMERGING ROLE IN DRUG DELIVERY APPLICATIONS-Reference-Cited by-同舟云学术

HYDROXYAPATITE NANOPARTICLES: A REVIEW OF THEIR EMERGING ROLE IN DRUG DELIVERY APPLICATIONS

Published:2024-03-15 Issue:2 Volume:8 Page:7-18
ISSN:2537-4761
Container-title:Annals of the Academy of Romanian Scientists Series on Physics and Chemistry
language:
Short-container-title:AnnalsARSciPhysChem

Author:

,PADURARU FILIP Diana-Georgiana,PADURARU Andrei-Viorel, ,ANDRONESCU Ecaterina, ,SURDU Adrian-Vasile,

Abstract

This literature review assesses existing research on hydroxyapatite-based drug delivery systems, with a focus on evaluating their effectiveness. Researchers are actively exploring strategies to enhance drug loading capacity, involving surface modifications of nanoparticles and the innovation of novel drug encapsulation techniques. Elevating drug loading has the potential to clearly increase the therapeutic efficacy of these systems. Stability issues also present a challenge in the clinical translation of nanoparticle-based drug delivery systems. Furthermore, scientists are underway to minimize potential side effects by judiciously selecting biocompatible materials for nanoparticle synthesis and conducting comprehensive toxicity studies before advancing to clinical trials.

Publisher

Academia Oamenilor de Stiinta din Romania

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