Detection of PML/RARA Rearrangement by Reverse Transcriptase-PCR and Sequencing in a Case of Microgranular Acute Promyelocytic Leukemia Lacking t(15;17) on Karyotype and FISH
Author:
Affiliation:
1. Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea
2. Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea
Funder
Ministry of Health and Welfare
Publisher
Annals of Laboratory Medicine
Subject
Biochemistry (medical),Clinical Biochemistry,General Medicine
Link
https://synapse.koreamed.org/pdf/10.3343/kjlm.2009.29.5.379
Reference16 articles.
1. Identification of PML–RARA rearrangement by RT-PCR and sequencing in an acute promyelocytic leukemia without t(15;17) on G-banding and FISH
2. Acute promyelocytic leukemia with i(17)(q10) on G-banding andPML/RARArearrangement by RT-PCR without evidence ofPML/RARArearrangement on FISH
3. New highly sensitive fluorescence in situ hybridization method to detect PML/RARA fusion in acute promyelocytic leukemia
4. The genetic characterization of acute promyelocytic leukemia with cryptic t(15;17) including a new recurrent additional cytogenetic abnormality i(17)(q10)
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1. A Case of Therapy-related Acute Promyelocytic Leukemia Lacking t(15;17) on Karyotype;Laboratory Medicine Online;2021-07-01
2. Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML and loss of one p53 gene: Report of two cases and literature review;Vojnosanitetski pregled;2019
3. Modified Array-based Comparative Genomic Hybridization Detects Cryptic and Variant PML-RARA Rearrangements in Acute Promyelocytic Leukemia Lacking Classic Translocations;Diagnostic Molecular Pathology;2013-03
4. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases;Annals of Hematology;2012-03-09
5. Microgranular variant of acute promyelocytic leukemia with normal conventional cytogenetics, negative PML/RARA FISH and positive PML/RARA transcripts by RT-PCR;Cancer Genetics;2011-09
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