Effect of genetic polymorphisms on effectiveness of low-dose azathioprine in Japanese patients with systemic lupus erythematosus-Reference-Cited by-同舟云学术

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Effect of genetic polymorphisms on effectiveness of low-dose azathioprine in Japanese patients with systemic lupus erythematosus

Published:2012-12-01 Issue:23 Volume:69 Page:2072-2078
ISSN:1079-2082
Container-title:American Journal of Health-System Pharmacy
language:en
Short-container-title:

Author:

Nagamine Ayumu¹,Takenaka Miki¹,Aomori Tohru²,Okada Yuko³,Hiromura Keiju⁴,Nojima Yoshihisa⁴,Araki Takuya⁵,Nakamura Tomonori⁵,Yamamoto Koujirou⁶

Affiliation:

1. Department of Pharmacy Gunma University Hospital, Showa-machi, Maebashi, Japan.

2. Department of Clinical Pharmacology, Graduate School of Medicine, Gunma University, Showa-machi.

3. Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaoorui-machi, Takasaki, Japan.

4. Department of Medicine and Clinical Science

5. Department of Clinical Pharmacology

6. Department of Clinical Pharmacology, Graduate School of Medicine, Gunma University

Publisher

Oxford University Press (OUP)

Subject

Health Policy,Pharmacology

Link

http://academic.oup.com/ajhp/article-pdf/69/23/2072/28362113/ajhp2072.pdf

Reference34 articles.

1. Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review;Gisbert;Am J Gastroenterol.,2008

2. Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease;Takatsu;J Gastroenterol Hepatol.,2009

3. Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease;Lees;Aliment Pharmacol Ther.,2008

4. Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease;Winter;Aliment Pharmacol Ther.,2007

5. The clinical pharmacology of 6-mercaptopurine;Lennard;Eur J Clin Pharmacol.,1992

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. XDH genotypes through gene–gene interactions with NUDT15 affect azathioprine-induced leukopenia in Chinese patients;Pharmacogenomics;2022-08

2. Severe thiopurine-induced leukocytopenia and hair loss in Japanese patients with defectiveNUDT15 variant: Retrospective case-control study;The Journal of Dermatology;2018-08-13

3. A novel ABCC6 haplotype is associated with azathioprine drug response in myasthenia gravis;Pharmacogenetics and Genomics;2017-02

4. Effect of genetic polymorphisms of azathioprine-metabolizing enzymes on response to rheumatoid arthritis treatment;PHARMAZIE;2017

5. Efficacy and safety of tabalumab plus standard of care in Japanese patients with active systemic lupus erythematosus: Subgroup analyses of the ILLUMINATE-1 study;Modern Rheumatology;2016-07-29

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