Treatment of local-anesthetic toxicity with lipid emulsion therapy

Author:

Burch Melissa S.1,McAllister Russell K.2,Meyer Tricia A.3

Affiliation:

1. Department of Anesthesiology, Scott and White Memorial Hospital (SWMH), Temple, TX, and Resident Physician, College of Medicine, Texas A&M Health Science Center (HSC), College Station.

2. College of Medicine, Texas A&M HSC, and Staff Physician, Department of Anesthesiology, SWMH.

3. College of Medicine, Texas A&M HSC, and Director of Pharmacy, Department of Pharmacy, SWMH

Publisher

Oxford University Press (OUP)

Subject

Health Policy,Pharmacology

Reference18 articles.

1. Fatalities from local anesthetics;Mayer;JAMA,1928

2. Bupivacaine inhibits acylcarni-tine exchange in cardiac mitochondria;Weinberg;Anesthesiology,2000

3. Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart;Weinberg;Reg Anesth Pain Med,2006

4. Pretreatment of resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats;Weinberg;Anesthesiology,1998

5. Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity;Weinberg;Reg Anesth Pain Med,2003

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1. Effect of Intravenous Lipid Emulsion on Clozapine Acute Toxicity in Rats;Journal of Pharmacopuncture;2019-09-30

2. Emergency Response in the Ambulatory Surgery Center;Anesthesiology Clinics;2019-06

3. Introduction to surgical and perioperative clinical pharmacy for third-year pharmacy students: A pilot study of an elective course;Currents in Pharmacy Teaching and Learning;2018-03

4. Suspected synthetic cannabinoid toxicosis in a dog;Journal of Veterinary Emergency and Critical Care;2015-10-16

5. Local Anesthesia Toxicity and Lipid Rescue;Journal of PeriAnesthesia Nursing;2015-08

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