Cytochrome P–450 gene and drug interaction analysis in patients referred for pharmacogenetic testing

Author:

Hocum Brian Thomas1,White John Raymond2,Heck Jarrod W.1,Thirumaran Ranjit K.1,Moyer Nicolas1,Newman Richard1,Ashcraft Kristine1

Affiliation:

1. Genelex Corporation, Seattle, WA

2. Department of Pharmaco-therapy, College of Pharmacy, Washington State University, Spokane, WA

Publisher

Oxford University Press (OUP)

Subject

Health Policy,Pharmacology

Reference16 articles.

1. A systematic review and critical assessment of 11 discordant meta-analyses on reduced-function CYP2C19 genotype and risk of adverse clinical outcomes in clopidogrel users;Osnabrugge;Genet Med,2015

2. Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update;Scott;Clin Pharmacol Ther,2013

3. Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership. Plavix (clopidogrel bisulfate) prescribing information.http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=01b14603-8f29-4fa3-8d7e-9d523f802e0b (accessed 2015 Jun 14).

4. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future;Ingelman-Sundberg;Trends Pharmacol Sci,2004

5. Chapter 7: pharmacogenomics;Karczewski;PLoS Comput Biol,2012

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