CLINICAL SIGNIFICANCE OF VISCERAL OBESITY FOR PATIENTS WITH BRONCHIAL ASTHMA

Abstract

Visceral obesity plays an important role in chronic inflammation in asthma patients. This is due to the hormonal activity of visceral fat. The visceral adipose tissue (VAT) level is assessed using a number of methods, each of which has its own pros and cons. This study aimed to explore the associations of VAT tissue measured by bioelectrical impedance analysis with lipid metabolism and FEV1 in patients with asthma. Materials and methods. The study included 42 patients with asthma aged 19–52 years. The anthropometric parameters, lipid metabolism, VAT have been assessed. We used bioelectrical impedance analysis (BEI) to evaluate VAT level. Results. High levels of VAT were associated with increased levels of TG, total cholesterol, LDL, decreased levels of HDL. With an increase in VAT by 1% should expect a decrease in FEV1 by 1.08%. 43% of overweight patients had elevated VAT levels. At the same time, in 18% of obese patients, according to BMI, increased visceral fat was not detected. Conclusions. Visceral obesity is associated with the decrease of FEV1 and dyslipidemia of patients with asthma. It is recommended to include the level of VAT by BIA measurement method, in patients with asthma in the algorithms of the medical care to reduce the hypodiagnosis of visceral obesity in individuals with normal and subnormal BMI. Key words: bronchial asthma, visceral obesity, general obesity, visceral adipose tissue, bioelectrical impedance analysis.