Comparative Analysis of Haemolysin Production and Complement Levels in Indigenous Rabbits (Oryclolagus cunicali) and Other Animal Species

Abstract

The complement system is an essential part of the immune response, defending against infections and contributing to inflammation. This studyfocuses on haemolysin production and complement levels in local rabbits, using subcutaneous and intravenous inoculation. It also evaluatedcomplement levels in various animal species and healthy humans for comparison. Serum samples were collected, and the complement fixationtest was performed using sheep red blood cells as markers. The findings revealed changes in red blood cell lysis with different haemolysin dilutions over time. The study also provides information on complement minimum haemolytic dose concentrations in various animal species. A graph illustrates the antibody levels in response to different inoculation routes. This research enhances our understanding of haemolysin and complement levels, emphasizing the need for standardized protocols and larger population studies to explore clinical implications to benefit immunological studies.