Study of the Effect of Pentostam on Some Bacterial Species Isolated from Skin Infections

Abstract

In the current study, Pentostam treatment, used to treat cutaneous leishmaniasis, was used against some types of bacteria isolated from skin infections (Klebsiella and Staphylococcus) to determine the extent of the bacteria's resistance to this treatment. The results showed that staph bacteria were more sensitive than Klebsiella bacteria.  On the Mueller-Hinton medium and measuring the inhibition zone, some types of vitamins were used in this study, such as vitamin C and vitamin B, without and with Pentostam, to determine their effect in increasing or decreasing the effectiveness of Albutostam against bacteria.  The findings demonstrated that vitamin B did not affect the bacteria's sensitivity to vitamin C alone. However, when they were combined with pentostam treatment, the results showed that vitamin B had the effect of reducing the effectiveness of pentostam against staph. Bacteria and klebsiella bacteria, while vitamin C was shown to increase the effect of pentostam treatment on Both types of bacteria.