Influence of the Saccharomyces cerevisiae-based probiotic complex on gut microbiota, serum biochemistry, and circulating trace element and mineral levels in lactating dairy cows-Reference-Cited by-同舟云学术

Influence of the Saccharomyces cerevisiae-based probiotic complex on gut microbiota, serum biochemistry, and circulating trace element and mineral levels in lactating dairy cows

Published:2024-08 Issue: Volume: Page:1864-1871
ISSN:2231-0916
Container-title:Veterinary World
language:en
Short-container-title:Vet World

Author:

Sizova Elena A.¹^ORCID,Yausheva Elena V.²^ORCID,Nechitailo Ksenia S.¹^ORCID,Kamirova Aina M.²^ORCID,Ryazanceva Kristina V.²^ORCID,Shoshin Daniil E.¹^ORCID,Skalny Anatoly V.³^ORCID,Tinkov Alexey A.⁴^ORCID

Affiliation:

1. Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia, 460000; Scientific-Educational Center “Biological Systems and Nanotechnologies”, Orenburg State University, Orenburg, Russia, 460018.

2. Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia, 460000.

3. Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia, 460000; Center for Bioelementology and Human Ecology, IM Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia, 119991.

4. Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia, 460000; Center for Bioelementology and Human Ecology, IM Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia, 119991; Laboratory of Microbial Persistence and Symbiosis, Institute of Cellular and Intracellular Symbiosis, Russian Academy of Sciences, Orenburg, Russia, 460000.

Abstract

Background and Aim: The existing data demonstrate that gut microbiota is involved in regulating mineral metabolism in cattle, although the data are quite contradictory. The study aimed to evaluate Saccharomyces cerevisiae-based probiotic’s effects on gut microbiota, systemic metabolism, and dairy cows’ essential trace element and mineral body burden. Materials and Methods: Fifteen cows received a daily supplement of a 50 g S. cerevisiae-based probiotic, fortified with methionine, choline, eugenol, cinnamaldehyde, and Capsicum oleoresin, for a month. 16S metagenomic sequencing was used to evaluate the taxonomic features of fecal microbiota. Serum trace elements and minerals levels were determined through inductively coupled plasma mass spectrometry. Results: Supplementation with S. cerevisiae-based probiotic complex significantly increased alpha and beta diversity, as well as the abundance of Mediterranea and Clostridium IV within the Bacillota phylum, whereas that of Bacteroidota and specifically unclassified Bacteroidales and unclassified Oscillospiraceae decreased. Following probiotic supplementation with the S. cerevisiae-based complex, gut microbiota modulation led to a significant boost in circulating levels of calcium, copper, selenium, and zinc. Creatinine levels decreased while total cholesterol levels increased within normal limits in the serum analysis. Conclusion: The observed improvement in trace elements and minerals in dairy cows might be due to changes in intestinal microflora caused by supplementation. Therefore, probiotic supplementation in cattle may be considered a potential tool for improvement of mineral nutrition in cattle. However, the influence of probiotic treatment and modulation of mineral metabolism on milk productivity and overall performance in cattle is yet to be estimated. Keywords: gut microbiota, minerals, probiotic, Saccharomyces cerevisiae, trace elements.

Funder

Russian Science Foundation

Publisher

Veterinary World

Link

https://www.veterinaryworld.org/Vol.17/August-2024/24.pdf

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