Application of negative wound pressure therapy to skin grafts after coverage of uncertain granular sites: a case series

Abstract

The split thickness skin graft (STSG) is one of the most popular tools used in reconstructive surgery. Developed for the first time by Olier in 1872, with perpetually improving techniques, this graft has since facilitated the reconstruction of skin defects. Negative wound pressure therapy (NPWT) is a therapeutic procedure that has been widely used for decades; it stabilizes the wound environment, improves tissue perfusion by stimulating granulation and angiogenesis, and reduces bacterial load and, consequently, wound edema. This case series of 3 patients aimed to show the advantages of applying NPWT over STSGs after the coverage of uncertain granular sites. The intake rate was 95% on average, with rapid wound healing, no hematoma formation, no need for regrafting, and no pain or signs of infection.