Clinical characteristics and outcomes of anemic patients with coronary artery disease after percutaneous coronary intervention (systematic review)

Abstract

Objective: to explore clinical characteristics and the influence of anemic syndrome on long-term outcomes of patients with coronary artery disease underwent percutaneous coronary intervention (PCI). Review writing methodology. A systematic review was performed according to PRISMA methodology using PubMed, Google Scholar, eLibrary, CyberLeninka databases. Search depth —from 2000 to 2022. The review included 16 original studies. Conclusion. It was shown that the patients with PCI and anemia were older, predominantly male sex as compared with patients without anemic syndrome. The risk of adverse short- and long-term outcomes (myocardial infarction, stroke, major bleeding, cardiovascular and non-cardiovascular death) was significantly increased in anemic patients even with a slight decrease in hemoglobin according to WHO criteria (less than 130 g/lfor men and less than 120 g/l for women). But majority of patients were not fit with the criteria of light grade of anemia according federal clinical guidelines (hemoglobin 90-110 g/l). The influence of anemia on outcomes becomes the most significant 12 months after PCI.