Comparison Of The Efficacy Of Two Laser Types In Healing Of Full-Thickness Wound: An Experimental Study

Abstract

The aim of the study ― To investigate the effectiveness of pulsed laser with high intensity and laser with low intensity on a full-thickness wound in rats and to compare the effects of both laser types. Material and Methods ― Forty-five adult male rats were utilized in the present study. After anesthesia, wound of five cm2 was produced on dorsal aspect in each rat; then, the rats were randomly classified into three groups as follows: high power pulsating laser group (A) which received Nd: YAG laser with 1064 nm wavelength, low power laser group (B) which received GaAlAs laser with 830 nm wavelength, and control group (C) which received no treatment. Laser lights in groups (A) and (B) were introduced at an intensity of five joules per cm2 with a total energy of 25 joules for each wound area through the use of a scanning method and at a rate of 3 sessions per week for three weeks. Results ― At the end of treatment, better wound healing in form of more wound contraction and higher healing rate was elicited in both laser groups in comparison to wound healing in the control group, and there were no significantly different effects between both laser types. Conclusion ― At the intensity of five joules/cm2, both low-intensity and pulsating high-intensity lasers speed up the healing of the wound in rats, and there are no significant differences between their effects.