Characterizing The State Of Heart Rate Autonomic Regulation And EEG In Elderly Women With Falls Syndrome

Author:

Shiryaeva Taisiya P.1ORCID,Fedotov Denis M.1ORCID,Gribanov Anatoliy V.1ORCID,Deryabina Irina N.2ORCID,Krainova Irina N.3ORCID,Bagretsov Sergey F.1ORCID

Affiliation:

1. Northern (Arctic) Federal University named after M.V. Lomonosov, Arkhangelsk, Russia

2. Arkhangelsk Regional Clinical Hospital, Arkhangelsk, Russia

3. Arkhangelsk Regional Children's Clinical Hospital, Arkhangelsk, Russia

Abstract

Objective — The goal of our study was to evaluate the contribution of the central and autonomic nervous systems to the maintenance of postural balance in the elderly. Material and Methods ― This study included 120 healthy women 60-74 YO living in the community. They were distributed among two subgroups: (1) fallers (n=60) and (2) non-fallers (n=60). Fallers had falls in the past 12 months, while non-fallers had none. Walk tests were performed using Balance Master® posturography machine (NeuroCom, Natus, USA). The state of the central nervous system was assessed by Geodesic 300 EEG system (GSN; Electrical Geodesics, Inc.; Eugene, OR, USA). The state of the autonomic nervous system was assessed by the VNS-Spectrum (Neurosoft, Russia) via cardiointervalography. Results ― In Sit to Stand test, the postural sway velocity was higher (p=0.047) and the walking speed (p=0.008) in Tandem Walk test was lower in fallers, compared with non-fallers. The results of the Step Quick Turn test showed that the movement times of the left and right legs were longer for the fallers vs. non-fallers (p=0.044 and p=0.036, respectively), and postural sway values during turning left or right were higher in fallers as well (p=0.001 and p=0.003, correspondingly). At the same time, Step Up and Over test revealed that lift-up index values were higher in fallers vs. non-fallers (p=0.016). There were no statistically significant differences between the groups in the state of the autonomic nervous system. The absolute spectral power of the EEG was lower in the frontal region of the right hemisphere in the alpha and beta EEG bands in the study group, compared with the control. Conclusion ― A deterioration in the quality of performing complex motor actions and a decrease in postural control in elderly women with falls syndrome were which may have caused their postural instability. Our results confirmed the need for early assessment of the dynamic components of postural control to prevent the development of falls as a geriatric syndrome.

Publisher

LLC Science and Innovations

Subject

General Medicine

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