Cardiohemodynamics and gas analysis rearrangements in response to re-breathing in young males of Russia’s Fareast

Abstract

The objective of this study was to examine the changes occurred in the heart rate variability, cardiovascular system and gas analysis in response to the test with return breathing in young Caucasian and Native men residing in Magadan region and Chukotka Autonomous District. Methods — Total 345 young men were examined; of them 65 were Native people from Chukotka Autonomous District (ChAD) and 35 Natives from Magadan Region (MR) as well as Caucasians (48 from ChAD and 197 from MR, respectively). Results — Studies have shown that in response to the hypoxic-hypercapnic effect, there were changes in the cardiovascular system, heart rate and gas analysis, with a number of differences depending on ethnicity and the region of residence. Region-related features of cardiohemodynamics were manifested by a more pronounced increase in the systolic blood pressure and heart rate in response to the re-breathing test in the two ethnic groups living in ChAD, which was observed against the background of higher values of the difference “baseline-test” in carbon dioxide levels in the exhaled air. Ethnic differences in our studies were seen due to the pronounced increase in response to the test for the activity of the parasympathetic link of the autonomic nervous system (increased TP and HF), at the background of a decrease in VLF observed only among Caucasians, which was associated with the lowest oxygen concentration in the exhaled air at the peak of the test. It was found that the significant differences in gas analysis identified at rest and at the peak of the test as well as rearrangements of the heart rate and cardiovascular system characteristics in response to the re-breathing in the young subjects residing in different regions of northeast Russia and belonging to different ethnic groups can serve as informative criteria reflecting the region caused ethnic characteristics of the organism. Conclusion — It was found, the most visible and informative parameters for the differences in dynamics of the studied systems demonstrated by the subjects of the two ethnic groups in the two observed regions of the Far East in response to a hypoxic-hypercapnic test with return breathing have been the spectral characteristics of the heart rate (TP, HF, VLF) and gas analysis with the calculation of the difference between the baseline and the peak values (difference in the CO2 and O2 concentration of the test-baseline).