Affiliation:
1. Republican Clinical Hospital (Kazan ); Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education
2. Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education
Abstract
Kidney transplantation is an effective method of treating patients with end-stage chronic renal failure, as it improves the quality of life and has advantages in patient survival compared with dialysis methods of substitutive renal therapy. To date, ultrasound examination (ultrasound) is the most common diagnostic method for assessing the morphological state of a kidney transplant. Shear wave ultrasound elastography serves as an additional method for assessing the stiffness of the renal allograft parenchyma and early diagnosis of its dysfunction. The aim of the study was to determine the correlation dependence of blood flow parameters, laboratory parameters and stiffness of the kidney transplant parenchyma at different periods. Materials and methods. The study group included 112 patients aged 18 to 59 years who underwent kidney transplantation. Each patient underwent ultrasound examination in B-mode and color Doppler imaging mode. The stiffness of the renal transplant parenchyma was determined using shear wave ultrasound elastography. The functional state of the kidney transplant was assessed by blood serum creatinine and urea levels. Research results. Laboratory results were compared with parenchymal stiffness and renal graft resistance index. In the early postoperative period, a moderate correlation was found (rxy = 0.301) between creatinine level and parenchymal stiffness and a weak correlation (rxy > 0.3) between creatinine level and resistance index, as well as between urea level and resistance index and parenchymal stiffness. Conclusions. Ultrasound examination makes it possible to evaluate hemodynamics in kidney transplants at different periods, which correlates with urea and creatinine levels in blood serum.
Publisher
I.N. Ulianov Chuvash State University
Reference10 articles.
1. Bakazova N.K., Kaliev R.R., Zhumagaziev T.S. Rol’ ul’trazvukovoi diagnostiki v otsenke sosudistykh oslozhnenii u retsipientov s pochechnym [The role of ultrasound diagnostics in the assessment of vascular complications in kidney transplant recipients]. Nauka, novye tekhnologii i innovatsii Kyrgyzstana, 2023, no. 6, pp. 158–161.
2. Shabunin A.V., Drozdov P.A., Makeev D.A. et al. Vliyanie eliminatsii vtorichnoi teplovoi ishemii na funktsiyu pochechnogo transplantata: eksperiment i klinicheskoe issledovanii [Effect of elimination of secondary warm ischemia on renal graft function: experiment and clinical study]. Vestnik transplantologii i iskusstvennykh organov, 2023, vol. 25, no. 2, pp. 26–37.
3. Galeev Sh.R., Gafurova E.R. Rol’ ul’trazvukovogo issledovaniya v kompleksnoi otsenke funktsional’nogo sostoyaniya transplantirovannoi pochki [The role of ultrasound in a comprehensive assessment of the functional state of a transplanted kidney]. Vestnik sovremennoi klinicheskoi meditsiny, 2009, vol. 2, iss. 3, pp. 5–7.
4. Sandrikov V.A., Kaabak M.M., Platonova E.N. et al. Rannie diagnosticheskie kriterii kriza ottorzheniya pochechnogo transplantata po dannym ul’trazvukovogo monitoringa [Early diagnostic criteria for a renal graft rejection crisis according to ultrasound monitoring. Transplantologiya, 2017, vol. 9, no. 3, pp. 248–251. DOI: 10.23873/2074-0506-2017-9-3-248-251.
5. Tukhbatullin M.G., Galeev Sh.R., Garifullina L.I., Galeev R.Kh. Ul’trazvukovaya elastografiya sdvigovoi volnoi v otsenke sostoyaniya pochechnogo transplantata [Shear wave ultrasound elastography in assessing the condition of a renal graft]. Sovremennye tekhnologii v meditsine, 2017, vol. 9, no. 4. pp. 131–136. DOI: 10.17691/stm2017.9.4.16.