Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity-Reference-Cited by-同舟云学术

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Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity

Published:2005-02 Issue:2 Volume:15 Page:105-113
ISSN:1744-6872
Container-title:Pharmacogenetics and Genomics
language:en
Short-container-title:Pharmacogenetics and Genomics

Author:

Lee Sang Seop,Jeong Hye-Eun,Liu Kwang-Hyeon,Ryu Ji-Young,Moon Taesung,Yoon Chang No,Oh S. June,Yun Chul-Ho,Shin Jae-Gook

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference30 articles.

1. Molecular Cloning and Expression of CYP2J2, a Human Cytochrome P450 Arachidonic Acid Epoxygenase Highly Expressed in Heart

2. Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

3. [42] Cytochrome P450 arachidonic acid epoxygenase: Stereochemical characterization of epoxyeicosatrienoic acids

4. Metabolism of Arachidonic Acid by Rat Adrenal Glomerulosa Cells: Synthesis of Hydroxyeicosatetraenoic Acids and Epoxyeicosatrienoic Acids*

5. Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase.

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1. The “outsized” role of the I‐helix kink in human Cytochrome P450s;Clinical and Translational Medicine;2023-09

2. Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro;Frontiers in Pharmacology;2023-05-23

3. Cardiomyocyte-specific CYP2J2 and its therapeutic implications;Expert Opinion on Drug Metabolism & Toxicology;2022-08-03

4. Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets;Signal Transduction and Targeted Therapy;2021-02-26

5. Molecular determinant of substrate binding and specificity of cytochrome P450 2J2;Scientific Reports;2020-12

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