SURGICAL OUTCOMES IN CONCURRENT SICKLE CELL AND DIABETIC RETINOPATHY

Author:

Rohowetz Landon J.1ORCID,Shaheen Abdulla1,Magraner Maria1,Flynn Harry W.1,Williams Basil K.1,Smiddy William E.1,Sridhar Jayanth1,Russell Jonathan F.2,Townsend Justin H.1,Berrocal Audina M.1,Albini Thomas1,Yannuzzi Nicolas A.1

Affiliation:

1. Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida; and

2. Department of Ophthalmology, University of Iowa, Iowa City, Iowa.

Abstract

Purpose: To report the clinical features and outcomes in eyes that underwent vitreoretinal surgery for complications of concurrent sickle cell retinopathy and diabetic retinopathy. Methods: Retrospective, consecutive case series of all eyes that underwent vitreoretinal surgery for complications secondary to concurrent sickle cell retinopathy and diabetic retinopathy between January 01, 2014, and December 31, 2021. Results: The study included 20 eyes of 14 patients. Indications for surgery included tractional retinal detachment in 12 eyes (60%), combined tractional retinal detachment/rhegmatogenous retinal detachment in 6 eyes (30%), and vitreous hemorrhage in 2 eyes (10%). Pars plana vitrectomy was performed in all eyes. One eye received a scleral buckle at the same time as pars plana vitrectomy. There was no change in mean best-corrected visual acuity at the last follow-up examination (1.5 [20/678]) when compared with mean preoperative best-corrected visual acuity (1.6 [20/762], P = 0.83). Preoperative best-corrected visual acuity correlated with postoperative best-corrected visual acuity at the last follow-up examination in eyes with retinal detachment (r = 0.49, P = 0.04). Single operation anatomic success was achieved in 11 of 17 eyes (65%) with retinal detachment. Conclusion: Functional and anatomic outcomes after surgery in eyes with concurrent sickle cell retinopathy and diabetic retinopathy are relatively poor.

Funder

National Institutes of Health

Research to Prevent Blindness

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference13 articles.

1. Variable practice patterns for management of sickle cell retinopathy;Mishra;Ophthalmol Retina,2021

2. Central and peripheral involvement of the retina in the initial stages of diabetic retinopathy;Santos;Retina,2024

3. Vitreoretinal management and surgical outcomes in proliferative sickle retinopathy: a case series;Chen;Am J Ophthalmol,2014

4. Visual outcome after vitrectomy for diabetic retinopathy. A five-year follow-up;Nakazawa;Acta Ophthalmol (Copenh),1993

5. Proliferative sickle cell retinopathy: outcomes of vitreoretinal surgery;Rohowetz;Ophthalmol Retina,2024

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