Author:
Costa Villela Ferreira Luiza,Braz Rodrigues da Silva Camila,de Pinho Lilia Gama,Lima Fernanda Vidigal Vilela,Dias Claudia Marques,Bahmad Fayez
Abstract
Objective
To report a case of Creutzfeldt-Jakob disease (CJD) that presented atypical initial manifestations and highlight the importance of complementary investigation to avoid diagnosis delay.
Patients
A 54-year-old female patient who presented with vertigo with positional nystagmus, nausea, and vomiting as initial CJD manifestations.
Intervention
Neuro-otological and brain magnetic resonance images, which showed abnormal hyperintense cortical signal in both hemispheres.
Main Outcome Measure
We reached a presumptive diagnosis of the prion disease after the first magnetic resonance imaging. Eventually, the patient presented with typical neurological findings and met the criteria for probable CJD.
Results
Our case report presents a patient with sporadic CJD who experienced dizziness as an initial manifestation and met the diagnostic criteria for probable CJD a few weeks after symptoms onset.
Conclusion
We believe that this case may serve to help otolaryngologists pay better attention to cases of dizziness associated with neurological signs and highlight the importance of complementary investigation using magnetic resonance imaging and neuro-otological tests to prevent delayed or incorrect diagnosis.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Neurology (clinical),Sensory Systems,Otorhinolaryngology