STK11 Adnexal Tumor: Exploring the Association With Peutz-Jeghers Syndrome and its Distinction From Morphologic Mimickers-Reference-Cited by-同舟云学术

STK11 Adnexal Tumor: Exploring the Association With Peutz-Jeghers Syndrome and its Distinction From Morphologic Mimickers

Published:2024-09-03 Issue: Volume: Page:
ISSN:1072-4109
Container-title:Advances in Anatomic Pathology
language:en
Short-container-title:

Author:

Bennett Jennifer A.¹^ORCID,Oliva Esther²

Affiliation:

1. Department of Pathology, University of Chicago, Chicago, IL

2. Department of Pathology, Massachusetts General Hospital, Boston, MA

Abstract

STK11 adnexal tumor is a novel malignant neoplasm of uncertain histogenesis frequently arising in a para-adnexal location and associated with Peutz-Jeghers syndrome in ∼50% of patients. Its broad morphologic spectrum and nonspecific immunohistochemical profile has resulted in misclassification in the past as a variety of other neoplasms including those of wolffian, sex cord-stromal, mesothelial, and epithelial derivation. This review focuses on the spectrum of adnexal neoplasms that may develop in Peutz-Jeghers syndrome, with particular emphasis on STK11 adnexal tumor and its differential diagnosis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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